Platelet integrin αIIbβ3: signal transduction, regulation, and its therapeutic targeting

Integrins are a family of transmembrane glycoprotein signaling receptors that can transmit bioinformation bidirectionally across the plasma membrane. Integrin αIIbβ3 is expressed at a high level in platelets and their progenitors, where it plays a central role in platelet functions, hemostasis, and...

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Dettagli Bibliografici
Pubblicato in:J Hematol Oncol
Autori principali: Huang, Jiansong, Li, Xia, Shi, Xiaofeng, Zhu, Mark, Wang, Jinghan, Huang, Shujuan, Huang, Xin, Wang, Huafeng, Li, Ling, Deng, Huan, Zhou, Yulan, Mao, Jianhua, Long, Zhangbiao, Ma, Zhixin, Ye, Wenle, Pan, Jiajia, Xi, Xiaodong, Jin, Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407232/
https://ncbi.nlm.nih.gov/pubmed/30845955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0709-6
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