Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome

Long QT syndrome (LQTS) is a heritable disease associated with ECG QT interval prolongation, ventricular tachycardia, and sudden cardiac death in young patients. Among genotyped individuals, mutations in genes encoding repolarizing K(+) channels (LQT1:KCNQ1; LQT2:KCNH2) are present in approximately...

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Autores principales: Brunner, Michael, Peng, Xuwen, Liu, Gong Xin, Ren, Xiao-Qin, Ziv, Ohad, Choi, Bum-Rak, Mathur, Rajesh, Hajjiri, Mohammed, Odening, Katja E., Steinberg, Eric, Folco, Eduardo J., Pringa, Ekatherini, Centracchio, Jason, Macharzina, Roland R., Donahay, Tammy, Schofield, Lorraine, Rana, Naveed, Kirk, Malcolm, Mitchell, Gary F., Poppas, Athena, Zehender, Manfred, Koren, Gideon
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2008
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373420/
https://ncbi.nlm.nih.gov/pubmed/18464931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33578
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