Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome

Long QT syndrome (LQTS) is a heritable disease associated with ECG QT interval prolongation, ventricular tachycardia, and sudden cardiac death in young patients. Among genotyped individuals, mutations in genes encoding repolarizing K(+) channels (LQT1:KCNQ1; LQT2:KCNH2) are present in approximately...

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Autors principals: Brunner, Michael, Peng, Xuwen, Liu, Gong Xin, Ren, Xiao-Qin, Ziv, Ohad, Choi, Bum-Rak, Mathur, Rajesh, Hajjiri, Mohammed, Odening, Katja E., Steinberg, Eric, Folco, Eduardo J., Pringa, Ekatherini, Centracchio, Jason, Macharzina, Roland R., Donahay, Tammy, Schofield, Lorraine, Rana, Naveed, Kirk, Malcolm, Mitchell, Gary F., Poppas, Athena, Zehender, Manfred, Koren, Gideon
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373420/
https://ncbi.nlm.nih.gov/pubmed/18464931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33578
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