Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome

Long QT syndrome (LQTS) is a heritable disease associated with ECG QT interval prolongation, ventricular tachycardia, and sudden cardiac death in young patients. Among genotyped individuals, mutations in genes encoding repolarizing K(+) channels (LQT1:KCNQ1; LQT2:KCNH2) are present in approximately...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Brunner, Michael, Peng, Xuwen, Liu, Gong Xin, Ren, Xiao-Qin, Ziv, Ohad, Choi, Bum-Rak, Mathur, Rajesh, Hajjiri, Mohammed, Odening, Katja E., Steinberg, Eric, Folco, Eduardo J., Pringa, Ekatherini, Centracchio, Jason, Macharzina, Roland R., Donahay, Tammy, Schofield, Lorraine, Rana, Naveed, Kirk, Malcolm, Mitchell, Gary F., Poppas, Athena, Zehender, Manfred, Koren, Gideon
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2008
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373420/
https://ncbi.nlm.nih.gov/pubmed/18464931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33578
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