RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice

Osteoclasts (OCs) function to reabsorb bone and are responsible for the bone loss associated with inflammatory arthritis and osteoporosis. OC numbers are elevated in most disorders of accelerated bone destruction, reflecting altered rates of precursor differentiation and apoptosis. Both of these pro...

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Detalhes bibliográficos
Main Authors: Vaira, Sergio, Alhawagri, Muhammad, Anwisye, Imani, Kitaura, Hideki, Faccio, Roberta, Novack, Deborah Veis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373419/
https://ncbi.nlm.nih.gov/pubmed/18464930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33392
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