RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice

Osteoclasts (OCs) function to reabsorb bone and are responsible for the bone loss associated with inflammatory arthritis and osteoporosis. OC numbers are elevated in most disorders of accelerated bone destruction, reflecting altered rates of precursor differentiation and apoptosis. Both of these pro...

Full description

Saved in:
Bibliographic Details
Main Authors: Vaira, Sergio, Alhawagri, Muhammad, Anwisye, Imani, Kitaura, Hideki, Faccio, Roberta, Novack, Deborah Veis
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373419/
https://ncbi.nlm.nih.gov/pubmed/18464930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33392
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items