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Alternative NF-κB Regulates RANKL-induced Osteoclast Differentiation and Mitochondrial Biogenesis via Independent Mechanisms

Mitochondrial biogenesis, the generation of new mitochondrial DNA and proteins, has been linked to osteoclast (OC) differentiation and function. In this study we used mice with mutations in key alternative NF-κB pathway proteins, RelB and NIK, to dissect the complex relationship between mitochondria...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Zeng, Rong, Faccio, Roberta, Novack, Deborah V
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834842/
https://ncbi.nlm.nih.gov/pubmed/26094846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2584
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