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Alternative NF-κB Regulates RANKL-induced Osteoclast Differentiation and Mitochondrial Biogenesis via Independent Mechanisms

Mitochondrial biogenesis, the generation of new mitochondrial DNA and proteins, has been linked to osteoclast (OC) differentiation and function. In this study we used mice with mutations in key alternative NF-κB pathway proteins, RelB and NIK, to dissect the complex relationship between mitochondria...

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Bibliografiske detaljer
Udgivet i:J Bone Miner Res
Main Authors: Zeng, Rong, Faccio, Roberta, Novack, Deborah V
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4834842/
https://ncbi.nlm.nih.gov/pubmed/26094846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2584
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