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Directional and balancing selection in human beta-defensins

BACKGROUND: In primates, infection is an important force driving gene evolution, and this is reflected in the importance of infectious disease in human morbidity today. The beta-defensins are key components of the innate immune system, with antimicrobial and cell signalling roles, but also reproduct...

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Detalhes bibliográficos
Main Authors: Hollox, Edward J, Armour, John AL
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373304/
https://ncbi.nlm.nih.gov/pubmed/18416833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-113
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