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Conversion of cysteine to formylglycine: A protein modification in the endoplasmic reticulum

In sulfatases a C(α)-formylglycine residue is found at a position where their cDNA sequences predict a cysteine residue. In multiple sulfatase deficiency, an inherited lysosomal storage disorder, catalytically inactive sulfatases are synthesized which retain the cysteine residue, indicating that the...

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Autores principales: Dierks, Thomas, Schmidt, Bernhard, von Figura, Kurt
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC23670/
https://ncbi.nlm.nih.gov/pubmed/9342345
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