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Recombinant extracellular domain of the three major subunits of GABA(A) receptor show comparable secondary structure and benzodiazepine binding properties

The three most widely expressed subunits of the GABA(A) receptor are α(1), β(2), and γ(2) subunits, and the major isoform in the human brain is a pentameric receptor composed of 2α(1)2β(2)1γ(2). Previously, we overexpressed the extracellular domain Q28-R248 of GABA(A) receptor α(1) subunit. In the p...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Shi, Haifeng, Tsang, Shui Ying, Tse, Man Kit, Xu, Zhiwen, Xue, Hong
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2003
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366965/
https://ncbi.nlm.nih.gov/pubmed/14573876
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