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Two β-rich structural domains in GABA(A) receptor α(1) subunit with different physical properties: Evidence for multidomain nature of the receptor

The type A γ-aminobutyric acid (GABA(A)) receptor is a major inhibitory neurotransmitter-gated ion channel. Previously, we identified a membrane-proximal β-rich (MPBR) domain in fragment C166-L296 of GABA(A) receptor α(1) subunit, forming nativelike pentamers. In the present study, another structura...

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Detalhes bibliográficos
Main Authors: Shi, Haifeng, Tsang, Shui Ying, Zheng, Hui, Sturgis, James N., Xue, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373682/
https://ncbi.nlm.nih.gov/pubmed/12142460
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