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Topology characterization of a benzodiazepine-binding β-rich domain of the GABA(A) receptor α(1) subunit
Structural investigation of GABA(A) receptors has been limited by difficulties imposed by its trans-membrane-complex nature. In the present study, the topology of a membrane-proximal β-rich (MPB) domain in the C139–L269 segment of the receptor α(1) subunit was probed by mapping the benzodiazepine (B...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253290/ https://ncbi.nlm.nih.gov/pubmed/16195550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051555205 |
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