Topology characterization of a benzodiazepine-binding β-rich domain of the GABA(A) receptor α(1) subunit

Structural investigation of GABA(A) receptors has been limited by difficulties imposed by its trans-membrane-complex nature. In the present study, the topology of a membrane-proximal β-rich (MPB) domain in the C139–L269 segment of the receptor α(1) subunit was probed by mapping the benzodiazepine (B...

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Autors principals: Xu, Zhiwen, Fang, Shisong, Shi, Haifeng, Li, Hoiming, Deng, Yiqun, Liao, Yinglei, Wu, Jiun-Ming, Zheng, Hui, Zhu, Huaimin, Chen, Hueih-Min, Tsang, Shui Ying, Xue, Hong
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2005
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253290/
https://ncbi.nlm.nih.gov/pubmed/16195550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051555205
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