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Recombinant extracellular domain of the three major subunits of GABA(A) receptor show comparable secondary structure and benzodiazepine binding properties
The three most widely expressed subunits of the GABA(A) receptor are α(1), β(2), and γ(2) subunits, and the major isoform in the human brain is a pentameric receptor composed of 2α(1)2β(2)1γ(2). Previously, we overexpressed the extracellular domain Q28-R248 of GABA(A) receptor α(1) subunit. In the p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366965/ https://ncbi.nlm.nih.gov/pubmed/14573876 |
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