Recombinant extracellular domain of the three major subunits of GABA(A) receptor show comparable secondary structure and benzodiazepine binding properties

The three most widely expressed subunits of the GABA(A) receptor are α(1), β(2), and γ(2) subunits, and the major isoform in the human brain is a pentameric receptor composed of 2α(1)2β(2)1γ(2). Previously, we overexpressed the extracellular domain Q28-R248 of GABA(A) receptor α(1) subunit. In the p...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shi, Haifeng, Tsang, Shui Ying, Tse, Man Kit, Xu, Zhiwen, Xue, Hong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2003
Gaiak:
For the Record
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366965/
https://ncbi.nlm.nih.gov/pubmed/14573876
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