XRCC1 and DNA polymerase β in cellular protection against cytotoxic DNA single-strand breaks

Single-strand breaks (SSBs) can occur in cells either directly, or indirectly following initiation of base excision repair (BER). SSBs generally have blocked termini lacking the conventional 5′Œ-phosphate and 3′Œ-hydroxyl groups and require further processing prior to DNA synthesis and ligation. XRC...

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Библиографические подробности
Главные авторы: Horton, Julie K, Watson, Mary, Stefanick, Donna F, Shaughnessy, Daniel T, Taylor, Jack A, Wilson, Samuel H
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366203/
https://ncbi.nlm.nih.gov/pubmed/18166976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2008.7
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