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XRCC1-mediated repair of strand breaks independent of PNKP binding
Repair of DNA-protein crosslinks and oxidatively damaged DNA base lesions generates intermediates with nicks or gaps with abnormal and blocked 3′-phosphate and 5′-OH ends that prevent the activity of DNA polymerases and ligases. End cleaning in mammalian cells by Tdp1 and PNKP produces the conventio...
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| Publicado no: | DNA Repair (Amst) |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5696015/ https://ncbi.nlm.nih.gov/pubmed/29100039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.10.007 |
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