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In vitro Induction of Myeloid Leukemia–Specific CD4 and CD8 T Cells by CD40 Ligand–Activated B Cells Gene Modified to Express Primary Granule Proteins
The primary granule proteins (PGP) of myeloid cells are a source of multiple antigens with immunotherapeutic potential for myeloid leukemias. Therefore, we developed a method to induce T-cell responses to PGP protein sequences. We found that gene-transfected antigen-presenting cells efficiently expa...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2366103/ https://ncbi.nlm.nih.gov/pubmed/15958635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-04-2363 |
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