CD34+ cells cultured in stem cell factor and interleukin-2 generate CD56+ cells with antiproliferative effects on tumor cell lines

In vitro stimulation of CD34+ cells with IL-2 induces NK cell differentiation. In order to define the stages of NK cell development, which influence their generation from CD34 cells, we cultured G-CSF mobilized peripheral blood CD34+ cells in the presence of stem cell factor and IL-2. After three we...

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Autores principales: Sconocchia, Giuseppe, Provenzano, Maurizio, Rezvani, Katayoun, Li, Jongming, Melenhorst, Jos, Hensel, Nancy, Barrett, A John
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087889/
https://ncbi.nlm.nih.gov/pubmed/15831091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-3-15
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