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Genetically engineered fixed K562 cells: potent “off the shelf” antigen presenting cells for generating virus specific T cells
BACKGROUND AIMS: The human leukemia cell line K562 represents an attractive platform for creating artificial antigen presenting cells (aAPC). It is readily expandable, does not express HLA class I and II and can be stably transduced with various genes. METHODS: In order to generate CMV antigen-speci...
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| Publié dans: | Cytotherapy |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6755681/ https://ncbi.nlm.nih.gov/pubmed/24176543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2013.08.008 |
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