Combined Inactivation of MYC and K-Ras Oncogenes Reverses Tumorigenesis in Lung Adenocarcinomas and Lymphomas

BACKGROUND: Conditional transgenic models have established that tumors require sustained oncogene activation for tumor maintenance, exhibiting the phenomenon known as “oncogene-addiction.” However, most cancers are caused by multiple genetic events making it difficult to determine which oncogenes or...

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Detaylı Bibliyografya
Asıl Yazarlar: Tran, Phuoc T., Fan, Alice C., Bendapudi, Pavan K., Koh, Shan, Komatsubara, Kim, Chen, Joy, Horng, George, Bellovin, David I., Giuriato, Sylvie, Wang, Craig S., Whitsett, Jeffrey A., Felsher, Dean W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2008
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365560/
https://ncbi.nlm.nih.gov/pubmed/18461184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002125
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