Characterization of an immortalizing N-terminal domain of polyomavirus large T antigen.
Polyomavirus large T antigen has an N-terminal domain of approximately 260 amino acids which can immortalize primary cells but lacks sequences known to be required for DNA binding and replication. Treatment of full-length large T with either V8 protease or chymotrypsin yields an N-terminal fragment...
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| 出版年: | J Virol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1994
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236501/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289370/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.2.668-673.1994 |
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