Characterization of an immortalizing N-terminal domain of polyomavirus large T antigen.

Polyomavirus large T antigen has an N-terminal domain of approximately 260 amino acids which can immortalize primary cells but lacks sequences known to be required for DNA binding and replication. Treatment of full-length large T with either V8 protease or chymotrypsin yields an N-terminal fragment...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Holman, P S, Gjoerup, O V, Davin, T, Schaffhausen, B S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC236501/
https://ncbi.nlm.nih.gov/pubmed/8289370
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