Characterization of an immortalizing N-terminal domain of polyomavirus large T antigen.
Polyomavirus large T antigen has an N-terminal domain of approximately 260 amino acids which can immortalize primary cells but lacks sequences known to be required for DNA binding and replication. Treatment of full-length large T with either V8 protease or chymotrypsin yields an N-terminal fragment...
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| Publicado no: | J Virol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC236501/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289370/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.68.2.668-673.1994 |
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