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The amino terminus of polyomavirus middle T antigen is required for transformation.

In polyomavirus-transformed cells, pp60c-src is activated by association with polyomavirus middle T antigen. These complexes have a higher tyrosine kinase activity compared with that of unassociated pp60c-src. Genetic analyses have revealed that the carboxy-terminal 15 amino acids of pp60c-src and t...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Cook, D N, Hassell, J A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1990
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC249341/
https://ncbi.nlm.nih.gov/pubmed/2157858
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