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The amino terminus of polyomavirus middle T antigen is required for transformation.

In polyomavirus-transformed cells, pp60c-src is activated by association with polyomavirus middle T antigen. These complexes have a higher tyrosine kinase activity compared with that of unassociated pp60c-src. Genetic analyses have revealed that the carboxy-terminal 15 amino acids of pp60c-src and t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Cook, D N, Hassell, J A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249341/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157858/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.5.1879-1887.1990
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