pp60c-src binding to polyomavirus middle T-antigen (MT) requires residues 185 to 210 of the MT sequence.

Interaction with the src family of tyrosine kinases is crucial to the transforming action of polyomavirus middle T-antigen (MT). Association with MT activates the tyrosine kinase activity of pp60(c-src) and, through subsequent MT phosphorylation, creates binding sites for signalling molecules whose...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Brewster, C E, Glover, H R, Dilworth, S M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5512-5520.1997
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