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pp60c-src binding to polyomavirus middle T-antigen (MT) requires residues 185 to 210 of the MT sequence.

Interaction with the src family of tyrosine kinases is crucial to the transforming action of polyomavirus middle T-antigen (MT). Association with MT activates the tyrosine kinase activity of pp60(c-src) and, through subsequent MT phosphorylation, creates binding sites for signalling molecules whose...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Brewster, C E, Glover, H R, Dilworth, S M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1997
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5512-5520.1997
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