The amino terminus of polyomavirus middle T antigen is required for transformation.
In polyomavirus-transformed cells, pp60c-src is activated by association with polyomavirus middle T antigen. These complexes have a higher tyrosine kinase activity compared with that of unassociated pp60c-src. Genetic analyses have revealed that the carboxy-terminal 15 amino acids of pp60c-src and t...
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| Udgivet i: | J Virol |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1990
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157858/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.5.1879-1887.1990 |
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