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Site-directed mutagenesis of polyomavirus middle-T antigen sequences encoding tyrosine 315 and tyrosine 250.

Tyrosine residues of middle-T and tyrosine phosphorylation are thought to be important in the transformation of cultured rodent cells by polyomavirus. Of the potential tyrosine sites in the carboxyl-terminal half of middle-T, tyrosines 297, 315, and 322 have been studied previously, whereas tyrosine...

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Udgivet i:J Virol
Principais autores: Markland, W, Oostra, B A, Harvey, R, Markham, A F, Colledge, W H, Smith, A E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2426465/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.59.2.384-391.1986
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