Human Enteric Microsomal CYP4F Enzymes O-Demethylate the Antiparasitic Prodrug Pafuramidine

Lignende værker

• CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]
  af: Wang, Michael Zhuo, et al.
  Udgivet: (2006)
• CYP1A1 and CYP1B1-mediated biotransformation of the antitrypanosomal methamidoxime prodrug DB844 forms novel metabolites through intramolecular rearrangement
  af: Ju, Wujian, et al.
  Udgivet: (2013)
• Participation of CYP2C8 and CYP3A4 in the N-demethylation of imatinib in human hepatic microsomes
  af: Nebot, Noelia, et al.
  Udgivet: (2010)
• Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4
  af: Foster, David J R, et al.
  Udgivet: (1999)
• A Semiphysiologically Based Pharmacokinetic Modeling Approach to Predict the Dose-Exposure Relationship of an Antiparasitic Prodrug/Active Metabolite Pair
  af: Yan, Grace Zhixia, et al.
  Udgivet: (2012)