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Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells

Ras is frequently mutated in cancer, and novel therapies are being developed to target Ras signalling. To identify non-invasive surrogate markers of Ras activation and inhibition, we used(31)P magnetic resonance spectroscopy (MRS) and investigated NIH 3T3 cells compared to a mutant ras transfected c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ronen, S M, Jackson, L E, Beloueche, M, Leach, M O
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363797/
https://ncbi.nlm.nih.gov/pubmed/11237392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1663
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