Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells

Ras is frequently mutated in cancer, and novel therapies are being developed to target Ras signalling. To identify non-invasive surrogate markers of Ras activation and inhibition, we used(31)P magnetic resonance spectroscopy (MRS) and investigated NIH 3T3 cells compared to a mutant ras transfected c...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ronen, S M, Jackson, L E, Beloueche, M, Leach, M O
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2001
Sujets:
Regular Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363797/
https://ncbi.nlm.nih.gov/pubmed/11237392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1663
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