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Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells
Ras is frequently mutated in cancer, and novel therapies are being developed to target Ras signalling. To identify non-invasive surrogate markers of Ras activation and inhibition, we used(31)P magnetic resonance spectroscopy (MRS) and investigated NIH 3T3 cells compared to a mutant ras transfected c...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363797/ https://ncbi.nlm.nih.gov/pubmed/11237392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1663 |
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