Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells

Ras is frequently mutated in cancer, and novel therapies are being developed to target Ras signalling. To identify non-invasive surrogate markers of Ras activation and inhibition, we used(31)P magnetic resonance spectroscopy (MRS) and investigated NIH 3T3 cells compared to a mutant ras transfected c...

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Bibliografski detalji
Glavni autori: Ronen, S M, Jackson, L E, Beloueche, M, Leach, M O
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2001
Teme:
Regular Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363797/
https://ncbi.nlm.nih.gov/pubmed/11237392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1663
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