Clinical pharmacokinetic and in vitro combination studies of nolatrexed dihydrochloride (AG337, Thymitaq(TM)) and paclitaxel

A clinical study of nolatrexed dihydrochloride (AG337, Thymitaq(TM)) in combination with paclitaxel was performed. The aims were to optimize the schedule of administration and determine any pharmacokinetic (PK) interactions between the two drugs. In vitro combination studies were performed to assist...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hughes, A N, Griffin, M J, Newell, D R, Calvert, A H, Johnston, A, Kerr, B, Lee, C, Liang, B, Boddy, A V
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2000
Aiheet:
Regular Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363406/
https://ncbi.nlm.nih.gov/pubmed/10789718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1172
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