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Clinical pharmacokinetic and in vitro combination studies of nolatrexed dihydrochloride (AG337, Thymitaq(TM)) and paclitaxel

A clinical study of nolatrexed dihydrochloride (AG337, Thymitaq(TM)) in combination with paclitaxel was performed. The aims were to optimize the schedule of administration and determine any pharmacokinetic (PK) interactions between the two drugs. In vitro combination studies were performed to assist...

詳細記述

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書誌詳細
主要な著者: Hughes, A N, Griffin, M J, Newell, D R, Calvert, A H, Johnston, A, Kerr, B, Lee, C, Liang, B, Boddy, A V
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363406/
https://ncbi.nlm.nih.gov/pubmed/10789718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1172
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