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A phase I study of nolatrexed dihydrochloride in children with advanced cancer. A United Kingdom Children's Cancer Study Group Investigation
A phase I study of nolatrexed, administered as a continuous 5 day intravenous infusion every 28 days, has been undertaken for children with advanced malignancy. 16 patients were treated at 3 dose levels; 420, 640 and 768 mg/m(2) 24 h(−1). 8 patients were evaluable for toxicity. In the 6 patients tre...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363615/ https://ncbi.nlm.nih.gov/pubmed/11139306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1569 |
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