Clinical pharmacokinetic and in vitro combination studies of nolatrexed dihydrochloride (AG337, Thymitaq(TM)) and paclitaxel

A clinical study of nolatrexed dihydrochloride (AG337, Thymitaq(TM)) in combination with paclitaxel was performed. The aims were to optimize the schedule of administration and determine any pharmacokinetic (PK) interactions between the two drugs. In vitro combination studies were performed to assist...

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Dades bibliogràfiques
Autors principals: Hughes, A N, Griffin, M J, Newell, D R, Calvert, A H, Johnston, A, Kerr, B, Lee, C, Liang, B, Boddy, A V
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2000
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2363406/
https://ncbi.nlm.nih.gov/pubmed/10789718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1172
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