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De-Orphaning the Structural Proteome through Reciprocal Comparison of Evolutionarily Important Structural Features

Function prediction frequently relies on comparing genes or gene products to search for relevant similarities. Because the number of protein structures with unknown function is mushrooming, however, we asked here whether such comparisons could be improved by focusing narrowly on the key functional f...

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Detalhes bibliográficos
Main Authors: Ward, R. Matthew, Erdin, Serkan, Tran, Tuan A., Kristensen, David M., Lisewski, Andreas Martin, Lichtarge, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362850/
https://ncbi.nlm.nih.gov/pubmed/18461181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002136
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