Prediction of enzyme function based on 3D templates of evolutionarily important amino acids

BACKGROUND: Structural genomics projects such as the Protein Structure Initiative (PSI) yield many new structures, but often these have no known molecular functions. One approach to recover this information is to use 3D templates – structure-function motifs that consist of a few functionally critica...

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Detalhes bibliográficos
Principais autores: Kristensen, David M, Ward, R Matthew, Lisewski, Andreas Martin, Erdin, Serkan, Chen, Brian Y, Fofanov, Viacheslav Y, Kimmel, Marek, Kavraki, Lydia E, Lichtarge, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219985/
https://ncbi.nlm.nih.gov/pubmed/18190718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-17
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