Prediction of enzyme function based on 3D templates of evolutionarily important amino acids

BACKGROUND: Structural genomics projects such as the Protein Structure Initiative (PSI) yield many new structures, but often these have no known molecular functions. One approach to recover this information is to use 3D templates – structure-function motifs that consist of a few functionally critica...

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Bibliografiske detaljer
Main Authors: Kristensen, David M, Ward, R Matthew, Lisewski, Andreas Martin, Erdin, Serkan, Chen, Brian Y, Fofanov, Viacheslav Y, Kimmel, Marek, Kavraki, Lydia E, Lichtarge, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219985/
https://ncbi.nlm.nih.gov/pubmed/18190718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-17
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