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Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N

SREBP cleavage activating protein (SCAP), a membrane-bound glycoprotein, regulates the proteolytic activation of sterol regulatory element binding proteins (SREBPs), which are membrane-bound transcription factors that control lipid synthesis in animal cells. SCAP-stimulated proteolysis releases acti...

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Bibliografski detalji
Glavni autori: Nohturfft, Axel, Brown, Michael S., Goldstein, Joseph L.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC23627/
https://ncbi.nlm.nih.gov/pubmed/9789003
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