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Restoration of p16(INK4A) protein induces myogenic differentiation in RD rhabdomyosarcoma cells
p16(INK4A) (p16) tumour suppressor induces growth arrest by inhibiting function of cyclin-dependent kinase (CDK)4 and CDK6. Homozygous p16 gene deletion is frequent in primary rhabdomyosarcoma (RMS) cells as well as derived cell lines. To confirm the significance of p16 gene deletion in tumour biolo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362237/ https://ncbi.nlm.nih.gov/pubmed/10098732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690165 |
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