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Aberrant DNA methylation of the p16(INK4a) gene in plasma DNA of breast cancer patients
Hypermethylation of exon 1 of p16(INK4a) was examined in tumour and plasma DNA of a series of breast cancer patients. De novo methylation was observed in the tumours of eight patients (23%), and in plasma DNA in five (14%) of these eight patients. Our data show that de novo methylation of exon 1 of...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362379/ https://ncbi.nlm.nih.gov/pubmed/10376981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690495 |
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