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Aberrant methylation of RASSF1A in plasma DNA prior to breast cancer diagnosis in the Breast Cancer Family Registry
In addition to classical genetic mechanisms such as deletions and mutations, growth regulatory genes can be inactivated via methylation of cytosine-residues in their promoter regions. Hypermethylation of promoter CpG islands is now recognized as an important and early event in carcinogenesis. Detect...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791602/ https://ncbi.nlm.nih.gov/pubmed/19755643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-1237 |
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