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Aberrant methylation of RASSF1A in plasma DNA prior to breast cancer diagnosis in the Breast Cancer Family Registry

In addition to classical genetic mechanisms such as deletions and mutations, growth regulatory genes can be inactivated via methylation of cytosine-residues in their promoter regions. Hypermethylation of promoter CpG islands is now recognized as an important and early event in carcinogenesis. Detect...

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Bibliografske podrobnosti
Main Authors: Yazici, Hulya, Terry, Mary Beth, Cho, Yoon Hee, Senie, Ruby T., Liao, Yuyan, Andrulis, Irene, Santella, Regina M.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791602/
https://ncbi.nlm.nih.gov/pubmed/19755643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-1237
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