XRCC1 polymorphisms and breast cancer risk from the New York Site of the Breast Cancer Family Registry: A family-based case-control study

BACKGROUND: XRCC1 is a scaffold protein involved in the early and late stages of Base Excision Repair (BER). Three DNA polymorphisms occur in XRCC1, resulting in non-synonymous amino acid changes, which could alter the binding or regulatory activities of XRCC1. MATERIALS AND METHODS: We used a famil...

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Hauptverfasser: Zipprich, Jennifer, Terry, Mary Beth, Brandt-Rauf, Paul, Freyer, Greg A., Liao, Yuyan, Agrawal, Meenakshi, Gurvich, Irina, Senie, Ruby, Santella, Regina M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications 2010
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862506/
https://ncbi.nlm.nih.gov/pubmed/20442803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.62535
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