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The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways
The Wild-type p53-induced phosphatase 1, Wip1 (or PPM1D), is unusual in that it is a serine/threonine phosphatase with oncogenic activity. A member of the type 2C phosphatases (PP2Cδ), Wip1 has been shown to be amplified and overexpressed in multiple human cancer types, including breast and ovarian...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer US
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2362138/ https://ncbi.nlm.nih.gov/pubmed/18265945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-008-9127-x |
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