Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations

The purpose of this study was to determine activity of temozolomide combined with paclitaxel or epothilone B in vitro, and to investigate the combination of temozolomide with paclitaxel in a Phase I clinical trial. Melanoma cell lines A375P and DX3 were treated with temozolomide and either paclitaxe...

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Detalhes bibliográficos
Main Authors: Azzabi, A, Hughes, A N, Calvert, P M, Plummer, E R, Todd, R, Griffin, M J, Lind, M J, Maraveyas, A, Kelly, C, Fishwick, K, Calvert, A H, Boddy, A V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2005
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361941/
https://ncbi.nlm.nih.gov/pubmed/15756276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602438
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