Phase II Trial of Temozolomide Plus O(6)-Benzylguanine in Adults With Recurrent, Temozolomide-Resistant Malignant Glioma

PURPOSE: This phase II trial was designed to define the role of O(6)-benzylguanine (O(6)-BG) in restoring temozolomide sensitivity in patients with recurrent or progressive, temozolomide-resistant malignant glioma and to evaluate the safety of administering O(6)-BG in combination with temozolomide....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Quinn, Jennifer A., Jiang, Sara Xiaoyin, Reardon, David A., Desjardins, Annick, Vredenburgh, James J., Rich, Jeremy N., Gururangan, Sridharan, Friedman, Allan H., Bigner, Darell D., Sampson, John H., McLendon, Roger E., Herndon, James E., Walker, Amy, Friedman, Henry S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Clinical Oncology 2009
Aiheet:
Original Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667825/
https://ncbi.nlm.nih.gov/pubmed/19204199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.18.8417
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