Phase II Trial of Temozolomide Plus O(6)-Benzylguanine in Adults With Recurrent, Temozolomide-Resistant Malignant Glioma

PURPOSE: This phase II trial was designed to define the role of O(6)-benzylguanine (O(6)-BG) in restoring temozolomide sensitivity in patients with recurrent or progressive, temozolomide-resistant malignant glioma and to evaluate the safety of administering O(6)-BG in combination with temozolomide....

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書誌詳細
主要な著者: Quinn, Jennifer A., Jiang, Sara Xiaoyin, Reardon, David A., Desjardins, Annick, Vredenburgh, James J., Rich, Jeremy N., Gururangan, Sridharan, Friedman, Allan H., Bigner, Darell D., Sampson, John H., McLendon, Roger E., Herndon, James E., Walker, Amy, Friedman, Henry S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Clinical Oncology 2009
主題:
Original Reports
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667825/
https://ncbi.nlm.nih.gov/pubmed/19204199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.18.8417
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