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Phase 1 Trial of Temozolomide (TMZ) plus Irinotecan (CPT-11) plus O(6)-Benzylguanine (O(6)-BG) in Adults with Recurrent Malignant Glioma
BACKGROUND: This is a phase I clinical trial conducted with patients who had recurrent or progressive malignant glioma (MG). The trial was designed to determine the maximum tolerated dose (MTD) and toxicity of irinotecan (CPT-11) when administered with temozolomide (TMZ) and O(6)-benzylguanine (O(6)...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748258/ https://ncbi.nlm.nih.gov/pubmed/19402172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24336 |
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