Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations

The purpose of this study was to determine activity of temozolomide combined with paclitaxel or epothilone B in vitro, and to investigate the combination of temozolomide with paclitaxel in a Phase I clinical trial. Melanoma cell lines A375P and DX3 were treated with temozolomide and either paclitaxe...

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Bibliografiske detaljer
Main Authors: Azzabi, A, Hughes, A N, Calvert, P M, Plummer, E R, Todd, R, Griffin, M J, Lind, M J, Maraveyas, A, Kelly, C, Fishwick, K, Calvert, A H, Boddy, A V
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2005
Fag:
Clinical Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361941/
https://ncbi.nlm.nih.gov/pubmed/15756276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602438
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